LI Fong Yau Sam
National University of Singapore, Singapore
Abstract
This talk focuses on the design, synthesis, and characterization of single-atom nanozymes (SANs) with enzymatic mimicking activity, addressing the growing need for stable, cost-effective, and efficient artificial enzymes. SANs, with their high atom utilization and tuneable catalytic properties, represent a significant advancement in biomimetic catalysis. This research explores several distinct SAN systems, each tailored to mimic the catalytic activity of specific natural enzymes: galactose oxidase, carbonic anhydrase, and superoxide dismutase. Collectively, these results contribute to the field of artificial enzymes by advancing the design of single-atom catalysts with enzyme-like properties. These SANs not only replicate the catalytic prowess of natural enzymes but also overcome their inherent limitations, such as instability and high cost. The findings have broad implications, ranging from industrial catalysis to biomedical applications, and pave the way for future innovations in nanozyme research.
Speaker's Introduction
Prof. LI Fong Yau Sam is an Emeritus Professor at Department of Chemistry, National University of Singapore, and Fellow of the Royal Society of Chemistry. As a distinguished expert in the field of functional nanomaterials, he has made significant progresses in environmental science and technology. His research interests also include analytical chemistry, biosensors and metabolomics. In recent years, he has conducted studies on anti-fouling membranes, photocatalytic materials, and electrodes for electrochemical energy generation. He has authored/co-authored more than 470 publications in international peer review journals with an H-index of 71, and has filed over 20 U.S. patents. He also serves/has served on editorial advisory boards of several international scientific journals.
